Agilix - Genomics - Proteomics - Biochips

Agilix has succeeded in the breakthrough development of the first Whole Genome Universal DNA Microarray System. This system allows genomics researchers to obtain high throughput gene expression analysis for any organism. Using the patented FAAST (Fixed Address Analysis of Sequence Tags) system, all possible genes are candidates for detection because the gene sequence need not be known prior to analysis. FAAST employs a proprietary and novel universal microarray that eliminates the need for microarrays that are specific to any organism.

Agilix scientists have developed the most innovative multiplex labeling technology available. The Agilix revolutionary ZeptoLabeling0/00 technology has helped to overcome one of the most significant limitations in proteomics today. ZeptoLabeling technology utilizes versatile, small, discrete labels of a proprietary composition, achieving significantly higher multiplex labeling than current labeling techniques. The unique properties of ZeptoLabels allow the simultaneous measurement of more analytes than any commercially available system. ZeptoLabels can be attached using standard chemistry techniques to proteins of interest (Direct Labeling), or attached to highly specific recognition molecules such as antibodies (Indirect Labeling), or incorporated directly into an organism or pathway of interest (Fusion) using the cell's own protein production machinery. The unique properties of ZeptoLabels allow detection of multiple labels in complex biological samples, in solution, or in tissues. Importantly, accuracy is increased because measurement is accomplished in parallel, rather than through serial analysis.

In addition to these developing technologies, important advances in recent years have led to the development of bio-chips capable of the universal sequencing of DNA based on sequencing-by-hybridization (SBH) technology. This process employs synthetic oligos as probes for the detection of complementary sequence segments in DNA. After applying the SBH process, the complete sequence is derived using bioinformatics techniques.

• HOME
• LINKS